Maladaptive phenotypic plasticity in cardiac muscle growth is suppressed in high‐altitude deer mice
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چکیده
منابع مشابه
Phenotypic Plasticity in Skeletal Muscle
Anyone training for a marathon knows that although the goal may at first seem unattainable, with the correct exercise regime, even the least promising athlete will eventually cross the finish line. This remarkable phenotypic plasticity, which allows us to reshape our bodies within the strictures of our genetic make-up, has fascinated scientists for the last 3 decades. However, Hans Hoppeler exp...
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In vertebrates living at high altitude, arterial hypoxemia may be ameliorated by reversible changes in the oxygen-carrying capacity of the blood (regulated by erythropoiesis) and/or changes in blood-oxygen affinity (regulated by allosteric effectors of hemoglobin function). These hematological traits often differ between taxa that are native to different elevational zones, but it is often unkno...
متن کاملContributions of phenotypic plasticity to differences in thermogenic performance between highland and lowland deer mice.
Small mammals face especially severe thermoregulatory challenges at high altitude because the reduced O2 availability constrains the capacity for aerobic thermogenesis. Adaptive enhancement of thermogenic performance under hypoxic conditions may be achieved via physiological adjustments that occur within the lifetime of individuals (phenotypic plasticity) and/or genetically based changes that o...
متن کاملDevelopmental plasticity in aerobic performance in deer mice (Peromyscus maniculatus).
While several studies have examined the abiotic effects of altitude (low ambient temperatures and hypoxia) on the aerobic performance of small mammals, few have explored the effects of development and maturation at different altitudes on aerobic performance as adults. We examined the basal metabolism and aerobic performance of deer mice (Peromyscus maniculatus) under four different developmenta...
متن کاملPhenotypic plasticity in nematodes
Model systems, including C. elegans, have been successfully studied to understand the genetic control of development. A genotype's phenotype determines its evolutionary fitness in natural environments, which are typically harsh, heterogeneous and dynamic. Phenotypic plasticity, the process by which one genome can produce different phenotypes in response to the environment, allows genotypes to b...
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ژورنال
عنوان ژورنال: Evolution
سال: 2018
ISSN: 0014-3820,1558-5646
DOI: 10.1111/evo.13626